The Central Asian Journal of Nephrology (ISSN 3105-4145) aims to provide a platform for the dissemination of high-quality research, clinical studies and expert opinions in the field of nephrology. It is dedicated to improving the understanding, prevention, diagnosis and treatment of kidney diseases in Central Asia and beyond. The journal aims to promote collaboration between researchers, clinicians and healthcare professionals to address the unique challenges in nephrology faced by the Central Asian region, because of its same cultural and environment factors, genetic background and similar healthcare models.

Call for Publications

The Central Asian Journal of Nephrology invites researchers from all over the world, clinicians, healthcare professionals, and policymakers to submit manuscripts that contribute to advancing knowledge and practice in nephrology, accommodating its regional focus and the specialized field of nephrology, while ensuring relevance to both local and international audiences.

We welcome original research, reviews, case reports, and methodological papers that explore all aspects of kidney health and disease. Topics of interest include, but are not limited to:

Prevention, diagnosis, and management of acute and chronic kidney diseases
Dialysis and renal transplantation
Basic science research in nephrology
Epidemiological studies on kidney disease burden
Public health and policy innovations in nephrology
Applications of data science, digital health, and AI in nephrology
Real-world evidence, patient-centered outcomes, and healthcare equity

The journal seeks to disseminate high-quality, interdisciplinary research that enhances clinical practice, informs policy, and promotes kidney health across Central Asia and beyond.

We encourage submissions that reflect regional insights, cross-national collaborations, and innovative approaches to addressing the growing challenges of kidney diseases.

Submit your manuscript today and join us in shaping the future of nephrology in Central Asia and beyond.

CURRENT ISSUE

Volume 2, Issue 3, 2026

Case Report

An Unusual Complication in a Patient on CAPD – Retroperitoneal Hemorrhage: A Case Report

Yashaswini Saraswathi, Manjusha Yadla, Vikram Kumar, Srinivas Pathakala, Sreekanth Burri

Central Asian Journal of Nephrology, 2(3), 2026, cajn017, https://doi.org/10.63946/cajn/19557

ABSTRACT: Background: Hemoperitoneum is an infrequent but recognized complication of continuous ambulatory peritoneal dialysis (CAPD), most commonly attributable to abdominal trauma, gynecological causes (follicular cyst rupture, menstrual reflux, ovulation, endometriosis), or intraperitoneal sources such as hepatic or splenic cyst rupture, catheter-related trauma, and vascular anomalies. Hemoperitoneum originating from a retroperitoneal source, particularly cyst rupture in autosomal dominant polycystic kidney disease (ADPKD), is exceedingly rare and has been reported only twice previously in the literature.
Case Presentation: We describe a 45-year-old postmenopausal woman with a 20-year history of ADPKD and ESKD on CAPD, who presented with hemorrhagic peritoneal dialysate outflow followed by complete outflow obstruction, anasarca, and altered sensorium. Imaging demonstrated a large intraperitoneal collection with air foci alongside a separate lesser-sac collection, in the absence of any demonstrable retroperitoneal-to-peritoneal communication or active contrast extravasation. No alternative source of hemorrhage was identified after multidisciplinary evaluation. The patient was managed with temporary discontinuation of CAPD, hemodialysis via a non-tunneled internal jugular catheter, blood transfusion, and intraperitoneal antibiotic therapy, with gradual clinical improvement.
Conclusion: Retroperitoneal hemorrhage should be considered in the differential diagnosis of hemoperitoneum in patients with ADPKD on peritoneal dialysis. Prompt recognition of pain and hemorrhagic dialysate in this population is essential to enable timely intervention and salvage of the peritoneal dialysis modality.