CENTRAL ASIAN JOURNAL OF NEPHROLOGY
Case Report
Sep 15, 2025 13 2

Acute Tubulointerstitial Nephritis in a Patient Post-Renal Transplantation

Zhanna Kozybayeva 1 * ,
Aigerim Khabayeva 1,
Meruyert Madikenova 1,
Baknur Absattar 2,
Zhanat Kuanshaliyeva 1,
Nazym Nigmatullina 3
1 Department of Nephrology, University Medical Center, Astana, Kazakhstan2 Department of Medicine, School of Medicine, Nazarbayev University, Astana, Kazakhstan3 Department of Medicine, Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan * Corresponding Author
Central Asian Journal of Nephrology, 1(2), 2025, cajn006, https://doi.org/10.63946/cajn/16982
Publication date: Sep 15, 2025
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ABSTRACT

A 41-year old female patient who underwent kidney transplantation as an outcome of chronic glomerulonephritis came to the hospital with the signs of acute upper respiratory tract infection. As the patient further developed oliguria, peripheral edema, fever, and an increased BP, she was further relocated to the University Medical Center (UMC). Upon admission to UMC, signs of septic shock were detected, and acute transplant rejection was suspected, to exclude which kidney biopsy was performed and stage 3 chronic kidney disease (CKD) in allograft kidney was detected. Antibacterial treatment as well as pulse therapy were performed as patient had septic shock and tubulointerstitial nephritis (TIN).

KEYWORDS

Acute Tubulointerstitial Nephritis Renal Transplantation Kidney Transplant Complications Graft Dysfunction Transplant Nephropathy Immunosuppression Biopsy Findings Nephrology Renal Pathology Case Report.

CITATION (Vancouver)

Kozybayeva Z, Khabayeva A, Madikenova M, Absattar B, Kuanshaliyeva Z, Nigmatullina N. Acute Tubulointerstitial Nephritis in a Patient Post-Renal Transplantation. Central Asian Journal of Nephrology. 2025;1(2):cajn006. https://doi.org/10.63946/cajn/16982
APA
Kozybayeva, Z., Khabayeva, A., Madikenova, M., Absattar, B., Kuanshaliyeva, Z., & Nigmatullina, N. (2025). Acute Tubulointerstitial Nephritis in a Patient Post-Renal Transplantation. Central Asian Journal of Nephrology, 1(2), cajn006. https://doi.org/10.63946/cajn/16982
Harvard
Kozybayeva, Z., Khabayeva, A., Madikenova, M., Absattar, B., Kuanshaliyeva, Z., and Nigmatullina, N. (2025). Acute Tubulointerstitial Nephritis in a Patient Post-Renal Transplantation. Central Asian Journal of Nephrology, 1(2), cajn006. https://doi.org/10.63946/cajn/16982
AMA
Kozybayeva Z, Khabayeva A, Madikenova M, Absattar B, Kuanshaliyeva Z, Nigmatullina N. Acute Tubulointerstitial Nephritis in a Patient Post-Renal Transplantation. Central Asian Journal of Nephrology. 2025;1(2), cajn006. https://doi.org/10.63946/cajn/16982
Chicago
Kozybayeva, Zhanna, Aigerim Khabayeva, Meruyert Madikenova, Baknur Absattar, Zhanat Kuanshaliyeva, and Nazym Nigmatullina. "Acute Tubulointerstitial Nephritis in a Patient Post-Renal Transplantation". Central Asian Journal of Nephrology 2025 1 no. 2 (2025): cajn006. https://doi.org/10.63946/cajn/16982
MLA
Kozybayeva, Zhanna et al. "Acute Tubulointerstitial Nephritis in a Patient Post-Renal Transplantation". Central Asian Journal of Nephrology, vol. 1, no. 2, 2025, cajn006. https://doi.org/10.63946/cajn/16982

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