CENTRAL ASIAN JOURNAL OF NEPHROLOGY
Original Article
Dec 01, 2025 91 50

Study of the Prevalence and Risk Factors of Chronic Kidney Disease in the Kyrgyz Republic

Dinara Aiypova 1,
Asel Budaichieva 1 * ,
Saltanat Tatenova 1,
Taalaigul Omurbekova 1,
Yuliya Korolyova 1,
Sultanbek Kulubaev 1,
Rysbek Kaliev 1,
Ayzhan Kasmalieva 1 *
1 Department of Nephrology, National Center of Cardiology and Internal Medicine named after Academician M.Mirrakhimov, Bishkek, Kyrgyz Republic* Corresponding Author
Central Asian Journal of Nephrology, 1(2), 2025, cajn009, https://doi.org/10.63946/cajn/17472
Publication date: Dec 01, 2025
Full Text (PDF)

ABSTRACT

Background: Chronic kidney disease (CKD) is an increasing global health concern and a major contributor to cardiovascular morbidity and mortality. Although its global prevalence is estimated at about 13%, data from Central Asia are limited.
Objective: To assess the prevalence, structure, and key determinants of CKD among adults in the Kyrgyz Republic.
Methods: A population-based cross-sectional study was conducted among adults aged ≥18 years across different regions. CKD was defined according to Kidney Disease: Improving Global Outcomes (KDIGO) criteria as an estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m² and/or a urinary albumin-to-creatinine ratio (UACR) ≥30 mg/g. Disease severity was staged by eGFR and albuminuria categories. Logistic regression identified independent predictors of CKD.
Results: The overall CKD prevalence was 10.8%, comparable to global estimates. Prevalence increased with age, reaching 25.0% among participants ≥70 years, of whom 64.3% had reduced kidney function. CKD was more common in women than in men (p<0.001). Major etiologic factors included diabetes mellitus (29%), chronic glomerulonephritis (23%), chronic pyelonephritis (17%), and hypertension (10%). In multivariable analysis, diabetes, hypertension, dyslipidemia, obesity (BMI ≥30), and rural residence were independent predictors of CKD (p<0.05).
Conclusion: CKD is highly prevalent among adults in the Kyrgyz Republic. Risk factors align with international data, but regional patterns show higher rates of chronic glomerulonephritis and pyelonephritis. Strengthening early detection, integrating CKD screening into national health programs, and focusing on high-risk groups—older adults, women, and rural populations—are crucial to reducing the CKD burden in Kyrgyzstan.

KEYWORDS

Chronic Kidney Disease Prevalence Risk Factors Diabetes Hypertension Dyslipidemia Obesity Kyrgyz Republic Central Asia

CITATION (Vancouver)

Aiypova D, Budaichieva A, Tatenova S, Omurbekova T, Korolyova Y, Kulubaev S, et al. Study of the Prevalence and Risk Factors of Chronic Kidney Disease in the Kyrgyz Republic. Central Asian Journal of Nephrology. 2025;1(2):cajn009. https://doi.org/10.63946/cajn/17472
APA
Aiypova, D., Budaichieva, A., Tatenova, S., Omurbekova, T., Korolyova, Y., Kulubaev, S., Kaliev, R., & Kasmalieva, A. (2025). Study of the Prevalence and Risk Factors of Chronic Kidney Disease in the Kyrgyz Republic. Central Asian Journal of Nephrology, 1(2), cajn009. https://doi.org/10.63946/cajn/17472
Harvard
Aiypova, D., Budaichieva, A., Tatenova, S., Omurbekova, T., Korolyova, Y., Kulubaev, S., . . . Kasmalieva, A. (2025). Study of the Prevalence and Risk Factors of Chronic Kidney Disease in the Kyrgyz Republic. Central Asian Journal of Nephrology, 1(2), cajn009. https://doi.org/10.63946/cajn/17472
AMA
Aiypova D, Budaichieva A, Tatenova S, et al. Study of the Prevalence and Risk Factors of Chronic Kidney Disease in the Kyrgyz Republic. Central Asian Journal of Nephrology. 2025;1(2), cajn009. https://doi.org/10.63946/cajn/17472
Chicago
Aiypova, Dinara, Asel Budaichieva, Saltanat Tatenova, Taalaigul Omurbekova, Yuliya Korolyova, Sultanbek Kulubaev, Rysbek Kaliev, and Ayzhan Kasmalieva. "Study of the Prevalence and Risk Factors of Chronic Kidney Disease in the Kyrgyz Republic". Central Asian Journal of Nephrology 2025 1 no. 2 (2025): cajn009. https://doi.org/10.63946/cajn/17472
MLA
Aiypova, Dinara et al. "Study of the Prevalence and Risk Factors of Chronic Kidney Disease in the Kyrgyz Republic". Central Asian Journal of Nephrology, vol. 1, no. 2, 2025, cajn009. https://doi.org/10.63946/cajn/17472

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