Keyword: Central Asia
3 results found.
Original Article
Central Asian Journal of Nephrology, 2(1), 2026, cajn012, https://doi.org/10.63946/cajn/18298
ABSTRACT:
Background: To evaluate diabetic kidney disease (DKD) knowledge, attitudes, and practices (KAP) among adults with type 2 diabetes (T2D) in southern Kyrgyzstan.
Methods: A cross-sectional survey assessed DKD KAP among adults with T2D recruited from public healthcare facilities in Osh, Kyrgyzstan. We used a structured questionnaire guided by the Health Belief Model and the Health Locus of Control. We used multiple linear regression models to examine factors associated with KAP scores.
Results: A total of 207 adults participated (mean age 61.0 ± 10.7 years; 61.4% female). Although 91.3% identified healthcare workers as their most trusted information source, only 49.3% reported receiving DKD-related information from a healthcare provider. Only 13.5% recognized that early kidney damage does not cause pain. Despite generally positive attitudes towards kidney protective behaviors, 72.9% of participants reported low personal control over their health outcomes. In adjusted models, prior receipt of provider DKD information was the sole factor consistently associated with higher knowledge (β = 1.25, 95% CI 0.43–2.08, p = 0.003), attitudes (β = 3.11, 95% CI 1.61–4.61, p < 0.001), and practices (β = 3.99, 95% CI 2.26–5.71, p < 0.001).
Conclusion: Adults with T2D in southern Kyrgyzstan experience significant knowledge gaps and misconceptions regarding kidney protection, despite high trust and willingness to learn from healthcare providers. Prior provider-delivered information was associated with better practices, highlighting the need for structured DKD counseling that explicitly addresses misconceptions and aligns health messages with local beliefs to strengthen self-efficacy.
Methods: A cross-sectional survey assessed DKD KAP among adults with T2D recruited from public healthcare facilities in Osh, Kyrgyzstan. We used a structured questionnaire guided by the Health Belief Model and the Health Locus of Control. We used multiple linear regression models to examine factors associated with KAP scores.
Results: A total of 207 adults participated (mean age 61.0 ± 10.7 years; 61.4% female). Although 91.3% identified healthcare workers as their most trusted information source, only 49.3% reported receiving DKD-related information from a healthcare provider. Only 13.5% recognized that early kidney damage does not cause pain. Despite generally positive attitudes towards kidney protective behaviors, 72.9% of participants reported low personal control over their health outcomes. In adjusted models, prior receipt of provider DKD information was the sole factor consistently associated with higher knowledge (β = 1.25, 95% CI 0.43–2.08, p = 0.003), attitudes (β = 3.11, 95% CI 1.61–4.61, p < 0.001), and practices (β = 3.99, 95% CI 2.26–5.71, p < 0.001).
Conclusion: Adults with T2D in southern Kyrgyzstan experience significant knowledge gaps and misconceptions regarding kidney protection, despite high trust and willingness to learn from healthcare providers. Prior provider-delivered information was associated with better practices, highlighting the need for structured DKD counseling that explicitly addresses misconceptions and aligns health messages with local beliefs to strengthen self-efficacy.
Original Article
Central Asian Journal of Nephrology, 1(2), 2025, cajn009, https://doi.org/10.63946/cajn/17472
ABSTRACT:
Background: Chronic kidney disease (CKD) is an increasing global health concern and a major contributor to cardiovascular morbidity and mortality. Although its global prevalence is estimated at about 13%, data from Central Asia are limited.
Objective: To assess the prevalence, structure, and key determinants of CKD among adults in the Kyrgyz Republic.
Methods: A population-based cross-sectional study was conducted among adults aged ≥18 years across different regions. CKD was defined according to Kidney Disease: Improving Global Outcomes (KDIGO) criteria as an estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m² and/or a urinary albumin-to-creatinine ratio (UACR) ≥30 mg/g. Disease severity was staged by eGFR and albuminuria categories. Logistic regression identified independent predictors of CKD.
Results: The overall CKD prevalence was 10.8%, comparable to global estimates. Prevalence increased with age, reaching 25.0% among participants ≥70 years, of whom 64.3% had reduced kidney function. CKD was more common in women than in men (p<0.001). Major etiologic factors included diabetes mellitus (29%), chronic glomerulonephritis (23%), chronic pyelonephritis (17%), and hypertension (10%). In multivariable analysis, diabetes, hypertension, dyslipidemia, obesity (BMI ≥30), and rural residence were independent predictors of CKD (p<0.05).
Conclusion: CKD is highly prevalent among adults in the Kyrgyz Republic. Risk factors align with international data, but regional patterns show higher rates of chronic glomerulonephritis and pyelonephritis. Strengthening early detection, integrating CKD screening into national health programs, and focusing on high-risk groups—older adults, women, and rural populations—are crucial to reducing the CKD burden in Kyrgyzstan.
Objective: To assess the prevalence, structure, and key determinants of CKD among adults in the Kyrgyz Republic.
Methods: A population-based cross-sectional study was conducted among adults aged ≥18 years across different regions. CKD was defined according to Kidney Disease: Improving Global Outcomes (KDIGO) criteria as an estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m² and/or a urinary albumin-to-creatinine ratio (UACR) ≥30 mg/g. Disease severity was staged by eGFR and albuminuria categories. Logistic regression identified independent predictors of CKD.
Results: The overall CKD prevalence was 10.8%, comparable to global estimates. Prevalence increased with age, reaching 25.0% among participants ≥70 years, of whom 64.3% had reduced kidney function. CKD was more common in women than in men (p<0.001). Major etiologic factors included diabetes mellitus (29%), chronic glomerulonephritis (23%), chronic pyelonephritis (17%), and hypertension (10%). In multivariable analysis, diabetes, hypertension, dyslipidemia, obesity (BMI ≥30), and rural residence were independent predictors of CKD (p<0.05).
Conclusion: CKD is highly prevalent among adults in the Kyrgyz Republic. Risk factors align with international data, but regional patterns show higher rates of chronic glomerulonephritis and pyelonephritis. Strengthening early detection, integrating CKD screening into national health programs, and focusing on high-risk groups—older adults, women, and rural populations—are crucial to reducing the CKD burden in Kyrgyzstan.
Original Article
Central Asian Journal of Nephrology, 1(2), 2025, cajn007, https://doi.org/10.63946/cajn/17084
ABSTRACT:
Background: Chronic kidney disease (CKD) is a major global health challenge, yet population-based data from Central Asia are scarce. We conducted a population-based screening study to assess kidney function distribution and associated risk factors in Astana, Kazakhstan.
Methods: In March 2024, 636 adults were screened through convenience sampling at four major institutions in Astana. After excluding incomplete data, 569 participants were analyzed. Demographic, lifestyle, and clinical information were collected, and serum creatinine was used to estimate glomerular filtration rate (eGFR). Reduced renal function was defined as eGFR <90 mL/min/1.73 m². Group comparisons and logistic regression analyses were performed to identify risk factors for reduced renal function.
Results: The median age of participants was 46 years (IQR 33–55), and 79.8% were women. Median eGFR was 92.8 (IQR 79.8–111.3) mL/min/1.73 m²; 54.1% had eGFR ≥90, 42.4% had eGFR 60–89, and 3.5% had eGFR 45–59. Reduced renal function was more common among older adults, females and those with hypertension and heart failure. In multivariable analysis, older age and female sex were independent predictors of reduced renal function. Awareness was low: only 15.0% of individuals with eGFR 45–59 reported having CKD.
Conclusion: This study provides the population-based evidence on kidney function in Astana, Kazakhstan. Reduced renal function was common, particularly among older adults. Findings highlight the importance of population-based screening and targeted prevention strategies to address kidney health in Kazakhstan.
Methods: In March 2024, 636 adults were screened through convenience sampling at four major institutions in Astana. After excluding incomplete data, 569 participants were analyzed. Demographic, lifestyle, and clinical information were collected, and serum creatinine was used to estimate glomerular filtration rate (eGFR). Reduced renal function was defined as eGFR <90 mL/min/1.73 m². Group comparisons and logistic regression analyses were performed to identify risk factors for reduced renal function.
Results: The median age of participants was 46 years (IQR 33–55), and 79.8% were women. Median eGFR was 92.8 (IQR 79.8–111.3) mL/min/1.73 m²; 54.1% had eGFR ≥90, 42.4% had eGFR 60–89, and 3.5% had eGFR 45–59. Reduced renal function was more common among older adults, females and those with hypertension and heart failure. In multivariable analysis, older age and female sex were independent predictors of reduced renal function. Awareness was low: only 15.0% of individuals with eGFR 45–59 reported having CKD.
Conclusion: This study provides the population-based evidence on kidney function in Astana, Kazakhstan. Reduced renal function was common, particularly among older adults. Findings highlight the importance of population-based screening and targeted prevention strategies to address kidney health in Kazakhstan.